Natural actives from California's farm byproducts.
Sequential Bio recovers high-value botanical compounds from plant material that is usually burned, composted or hauled away. We start in the vineyards of Temecula Valley.
Grown in California
Our raw material comes from farms in Southern California. Domestic origin, short supply lines, and a source you can visit.
Made from byproducts
Pruned canes and other plant material already come off the land every season. We turn that material into ingredients instead of waste.
Built on bioprocess science
Our extraction and purification work draws on two decades of industrial biotechnology, from enzymes and fermentation to downstream separations.
Grapevine stilbenes from pruned vineyard canes
Grapevines make resveratrol and its relatives, the viniferins, to protect their own wood. Those compounds are most concentrated in the canes that growers cut off every winter.
We are developing a standardized grapevine stilbene ingredient for skin care and nutrition brands, produced in California from California-grown vines.
In development · talking with formulators- Source
- Winter-pruned canes
- Origin
- Temecula Valley, CA
- Actives
- Resveratrol, viniferins
Rooted in California agriculture
Southern California grows far more than grapes. Other California crop byproducts are in evaluation.
California farms already grow the raw material. We turn more of each harvest into something useful.
Sequential Bio LLC is a small biotechnology company based in Murrieta, in the heart of Southern California's wine country.
Founder Ron Huffman has spent about 20 years in industrial biotech R&D, working on enzymes, fermentation and downstream separations. Sequential Bio applies that experience to a simple idea: the plant material farms already produce each season holds valuable natural compounds, and recovering them should be practical, clean and local.
We work closely with growers, vineyard managers and ingredient buyers, and we are building our first product with them.
Two ways to work with Sequential Bio
Ingredient partners
Brands, formulators and distributors looking for a natural, domestically produced grape-derived active.
- Early input on specifications and formats
- Development samples for qualified partners
- Technical details available under NDA
Vineyard & grower partners
Wineries, vineyard managers and growers with pruned canes or other plant material they would rather not burn or haul.
- We collect and haul the material ourselves
- We follow your site and biosecurity rules
- We share what we find in your material
Murrieta, California